Making vaccine research more efficient and accurate.

Challenge

Mabtech sought to enhance the efficiency, user-friendliness, and accuracy of their key products like the FluoroSpot, ELISpot, and FociSpot readers. These improvements were crucial to strengthen their tools used in vaccine development and disease characterization amidst the global fight against diseases caused by viruses, bacteria, and parasites.

Solution

• Strategic R&D partnership: Since 2016, Qamcom has partnered with Mabtech, focusing on advancing the hardware, software, and systems of the products developed during this period.
• Software Enhancements: Qamcom devised two significant software updates: Artifact Removal and FociSpot Clustering, targeting key issues in immunoassay analysis.
  • Artifact Removal: This feature provides automatic elimination of visual artifacts like hair and cell clumps, improving spot counting accuracy and minimizing manual corrections.
  • FociSpot Clustering: With this update, researchers can now differentiate and analyze merged virus-infected cell clusters more effectively, leading to finer precision in results.
• User Experience (UX): Significant emphasis was placed on UX design to ensure that the software remained intuitive and straightforward, enabling researchers to access crucial data effortlessly.
• Industrial AI played an essential role in this project.

Outcome

The collaboration between Qamcom and Mabtech led to the development of state-of-the-art immunoassay readers that have tangibly improved research outcomes in vaccine development and disease diagnosis. These advancements have made the analysis more precise and efficient, significantly reducing the manual workload for researchers. Mabtech acknowledges the beneficial and enduring relationship with Qamcom, expressing high satisfaction with the delivered expertise, quality, and understanding in creating impactful products.

This partnership not only meets Mabtech's need for technical excellence but also contributes to the global healthcare community by enhancing the capability to combat infectious diseases.

"We have been working with Qamcom since the very beginning of the product development project and have established a long and advantageous relationship with them. We are very satisfied with the quality, high-level expertise, general understanding, and delivery of the work Qamcom has done for us in terms of hardware and software development. Together, we have created products that will make a significant difference for many people. That is something that makes me proud every day."
Jesper Larsson, Head of Instruments at Mabtech

Deep dive

Improving ELISpot and FlouroSpot analysis with artifact removal.

Background

Immunoassays are at the forefront of modern biomedical research and clinical diagnostics, enabling researchers and clinicians to measure immune responses with precision. These advanced techniques harness the power of antibodies to detect specific biomarkers, aiding in disease diagnosis and the development of new medicines.

Despite their significance, immunoassays often encounter challenges related to accuracy and reproducibility, particularly due to artifacts that can obscure results. Addressing this issue requires cutting-edge solutions that enhance assay performance and ensure reliability in critical research and healthcare applications.

Solution

Refining data for clearer insights
‍Qamcom, in collaboration with Mabtech, has developed an advanced artifact removal feature designed to optimize immunoassay data interpretation. This innovation ensures that unwanted artifacts such as hair, paper fibers, and cell clumps are filtered out, allowing researchers to obtain clean data and reliable results.

The feature is fully integrated into Mabtech’s products, IRIS and ASTOR, delivering direct value to their customers. This isn’t a proof of concept – it is a production-ready solution optimizing researchers’ workflows.

By leveraging expertise in AI and MedTech, Qamcom has integrated a state-of-the-art approach that refines immunoassay data, making results more reliable and actionable. This breakthrough supports Mabtech’s mission to push the boundaries of immunoassay technology and empower researchers with the most accurate tools available.

Outcome

With Qamcom’s artifact removal technology, Mabtech’s immunoassays now offer:

• Improved reproducibility – Increasing confidence in immunoassay outcomes by ensuring consistent and reliable experiment results.
• Optimized research & diagnostics – Providing scientists and clinicians with superior tools for studying immune responses.

By combining Mabtech’s immunoassay expertise with Qamcom’s technological innovations, this collaboration marks a significant step forward in biomedical research, paving the way for more accurate diagnostics and groundbreaking discoveries in immunology.

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Deep dive

More precise results with FociSpot clustering through Industrial AI.

Background

Accurately measuring the number of infectious viruses in a sample is critical for the development of effective treatments and vaccines. Immunoassays play a crucial role in this process, allowing researchers to detect and quantify virus particles with precision.

Mabtech specializes in producing immunoassays that enhance virology research. However, the process of analyzing FociSpots—small clusters of infected cells—can be complex, requiring advanced solutions to ensure accurate quantification and interpretation of results.

Solution

Refining data for enhanced virus detection
‍In collaboration with Mabtech, Qamcom has developed an advanced foci spot clustering technology that significantly improves virus quantification. This technology enables researchers to distinguish and classify infected cell clusters with high accuracy, ensuring reliable data for virology studies.

By leveraging expertise in image processing, machine learning, and biomedical analysis, Qamcom’s solution enhances the detection and quantification of foci spots, reducing manual errors and improving consistency in virus measurement. This breakthrough empowers researchers with a more precise and automated approach to studying viral infections.

Outcome

With the FociSpot clustering technology, Mabtech’s immunoassays now offer:

• Higher accuracy in virus quantification – Reducing variability and improving the reliability of infectious virus measurements.
• Enhanced data interpretation – Providing researchers with a clearer and more consistent understanding of viral behavior.
• Optimized workflows – Automating parts of the analysis to minimize manual effort and increase efficiency.

By combining Mabtech’s immunoassay expertise with Qamcom’s technological innovations, this collaboration represents a significant advancement in virology research, supporting the development of more effective treatments and vaccines